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Research Associate– Target Biology - (Job Code 2016RATB)

Description: We are currently seeking a Research Associate with experience in drug discovery to join our Target Biology group. Primary responsibilities will include the execution of established biochemical and cell-based assays for the characterization of drug candidates. Additional responsibilities will include assay development and general laboratory support.

Qualifications: Candidates must have a B. in cell biology, molecular biology, biochemistry, or a related discipline with experience in a drug discovery setting. The successful candidate will be a flexible and careful bench scientist who is eager to learn and excited by the challenges and rewards of working in a highly demanding start-up environment.

(Title and compensation will be commensurate with qualifications and experience.)

To apply, please send your résumé and cover letter to hr at rapharma dot com.

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Compliance Specialist, Quality Assurance - (Job Code 2016QA)

Description: We are seeking an experienced GMP compliance specialist to review and manage the compliance aspects of manufacturing documentation and to establish and maintain Quality systems and procedures. In particular, the Compliance Specialist will work internally with the Pharmaceutical Development group and externally with manufacturing vendors to ensure regulations and procedures are established, followed and documented as appropriate to the phase of development and adapted through drug development.

Qualifications: Candidates must have a minimum BS degree in biochemistry, chemistry, or a related discipline with 5 years of GMP regulated industry experience. Candidates must have a demonstrable track record of increasing responsibility in knowledge and application of GMPs to create and maintain compliant processes to match Ra Pharma’s manufacturing model.

Candidates should have:

  • hands-on working experience in either manufacturing or QC testing lab
  • knowledge of current Good Manufacturing Practices for product manufacture, filling and testing
  • knowledge of international guidances (EMA, ICH) and their application
  • management and interface skills with external vendors and QA
  • ability to work in team environment
  • highly organized, self-starter

Please send cover letter and resume to hr at rapharma dot com.

Salary and title commensurate with experience.

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Research Associate or Post-Doctoral Scientist, Chemical Biology - (Job Code RASCB2016)

Description: We are seeking a multi-talented and creative chemical biologist to help us further develop our Extreme DiversityTM platform for directly selecting drug-like macrocyclic peptides against a wide range of protein targets. In particular, this scientist will help optimize the translation of non-natural peptides through the engineering and directed evolution of the translation machinery. This exciting work requires a multi-disciplinary approach involving molecular biology, protein biochemistry, analytical chemistry, and protein biochemistry.

Qualifications: Candidates must have a PhD degree in biochemistry, chemistry, or a related discipline or a Master’s degree with 2 years of experience. Candidates must have a demonstrable history of success integrating chemistry and biology to solve challenging scientific or technological problems.

Candidates should have experience with protein engineering and directed evolution, as well as some or all of the following:

  • In vitro selection technologies like mRNA display, phage display, and SELEX
  • RNA biochemistry, including in vitro transcription and gel electrophoresis
  • High resolution LC-MS analysis of peptides
  • Bioinformatics analysis in Python, R, or a similar language
  • Basic synthetic organic chemistry

To apply, please send your résumé and cover letter to hr at rapharma dot com.

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Scientist-Target Biology - (Job Code TBS2016)

Description: We are currently seeking a Scientist with expertise in the innate immune system to join our Target Biology group. Primary responsibilities will include the design, development, and execution of biochemical and cell-based assays for the validation of therapeutic targets and characterization of drug candidates. Additional responsibilities will include developing expertise in biology of targets and disease areas of interest and using this knowledge to advance projects as a member of a project team.

Qualifications: Candidates must have a Ph.D. in cell biology, molecular biology, biochemistry, or a related discipline with demonstrated scientific expertise in the biology of the innate immune system. The successful candidate will be a flexible and careful scientist with leadership potential who is eager to learn and excited by the challenges and rewards of working in a highly demanding start-up environment.

(Title and compensation will be commensurate with qualifications and experience.)

To apply, please send your résumé and cover letter to hr at rapharma dot com.

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Ra Pharma™ is building a dynamic team of scientists to solve the most difficult problems in drug discovery today. We seek highly motivated individuals who enjoy working in a collaborative atmosphere and a goal-oriented environment.

Ra Pharma™ is an equal opportunity employer offering competitive cash and stock compensation, excellent employee benefits and the opportunity for personal and professional growth in an outstanding and intellectually challenging work environment.